The lymphatic and venous pathways for the outflow of thyroxine, iodoprotein and inorganic iodide from the thyroid gland

摘要

1. Baboons and cats were given radioactive iodine and, at varying times after the injection, samples of thyroid and non-thyroid lymph and of thyroid venous and peripheral venous blood were collected. The radioactive material in these samples was separated by paper chromatography or by differential precipitation and solvent extraction into three main fractions: inorganic iodide, iodoamino acid iodine and high molecular-weight material (retained at the origin of chromatograms and not extractable by butanol or ethanol). The latter was considered to be iodoprotein.